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It has been reported that the chemopreventive agent α-difluoromethylornithine is not able to efficiently block expression of many tumorigenesis-related genes, including kallikrein 6, in activated Ki-ras-expressing Caco-2 cells (Ignatenko et al, 2004).
DA D1 antagonists reduce acquisition and block expression of sensitisation, while DA D2 antagonists only affect expression with the intermediate and high dose.
All rely on GLT-1 expression at VTA astrocytes; when VTA astrocytes lack functional GLT-1, cued conditioning fails to produce learned avoidance, and also fails to block expression of cocaine CPP (Fig. 7g, h).
Led by cell biologist Michael White, the researchers used a library of silencing RNAs to block expression of every known gene in the human genome there are about 21,000 in only six weeks.
Constructs encoding siRNA can block expression of VCAM-1 in both corneal and vascular endothelial cells (in the latter case after cytokine stimulation).
Molecular biologists use antisense DNA or RNA fragments as powerful tools to block expression of specific target genes, and thereby assess gene function.
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We then expressed shits1 broadly in all pacemaker neurons but blocked expression in the LNv using the GAL4 repressor GAL80 (Table 1, cry24; pdfGAL80/+; UASshits1/+, [24]).
Jeter tagged Torre with his mitt in the sixth inning of a humiliating 16-3 loss to Toronto, and Torre's concrete-block expression never changed.
Treatment of MLL cells with the compound selectively inhibits H3K79 methylation and blocks expression of leukemogenic genes.
Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension.
Expression of the wt p53 gene was regulated by a system, which allowed or blocked expression p53 by absence or presence of tetracycline in the culture media.
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