Sentence examples for block dose from inspiring English sources

As expected, the simulations show that overall APD90 shortens with increasing ICaL blocker dose, whereas it is prolonged when increasing IKr block dose.

This corresponds to APD90 prolongation by 7.5, 10, 15, and 16% for IC50, 2× IC50, 10× IC50, and 30× IKr0 IKr block dose, respectively.

On the contrary, T-wave amplitude is mostly determined by IKr block dose, even though both ICaL and IKr decrease T-wave peak.

Indeed, the QT interval decreases from 315 ms in control to 265 ms (by 15%) for ICaL block dose of IC50, to 240 ms (by 23%) for 2× IC50, to 176 ms (by 44%) for 10× IC50 dose, and to 157 ms (by 57%) for ICaL block dose of 30× IC50.

By contouring the specific virtual structures and setting a "directional block" or "complete block," dose distributions can be limited to a local region and dose reductions to the ipsilateral or contralateral organs were achieved.

As shown in Figure 1 E H, the increased transmembrane potential gradient also results in higher values of the T-wave peak in the ECG, for 30× IC50 than for 10× ICaL ICaL block dose.

However, simulations show that increasing ICaL by 30% results in QT prolongation and an increase in the T-wave amplitude for all the considered Na block doses.

Figure 1 D– H displays ECG traces obtained for five ICaL block doses, for no IKr block (e.g. control, Figure 1 D), and IC50, 2× IC50, 10× IC50, 30× IC50 doses of IKr blocker.

The recently reported COMET trial found that the β1/β2/α1 receptor blocking agent carvedilol given in a relatively high β1-receptor blocking dose regimen was superior in mortality reduction to immediate release metoprolol given in a relatively low β1-receptor blocking dose schedule.

The last point on the right represents the administered blocking dose (6.7 mg/kg, n = 5).

A group of ApoE-KO mice was co-injected with blocking dose (10 nmol) of non-labelled tilmanocept.