Sentence examples for block death from inspiring English sources

Roche has made antibody drugs that block death receptor six and is testing them in mice with Alzheimer's symptoms to see if they block memory loss.

Antiapoptotic proteins block death signaling by antagonizing the actions of Bax/Bak through partially known mechanisms.

TRAIL treatment was included as a positive control to confirm the level of caspase-8 silencing was sufficient to block death ligand/death receptor-driven apoptosis.

As high expression of all c-FLIP isoforms is reported to block death receptor-mediated apoptosis, we followed a loss-of-function approach to determine specific functions of the different c-FLIP splice variants.

Since immunodeficiency virus-infected T cells die in vitro and in vivo (Li et al., 2005; Mattapallil et al., 2005), we explored macrophage recognition of this process by attempting to block death receptor-ligand interactions using published inhibitors.

On the other hand, all three thiol and non-thiol antioxidants significantly block death-inducing activity of adenanthin.

This demonstrates for the first time that cisplatin does not signal for death via the fas pathway, but it does initiate the mitochondrial stress pathway in neurons and that NGF blocks death upstream of bax redistribution.

cFlip is the only protein present in the mTRAIL-R DISC that is capable of blocking death receptor-mediated apoptosis.

Accordingly, BJAB target cells with a blocked death receptor pathway due to the expression of dominant-negative FADD did not undergo apoptosis upon paracrine expression of TRAIL.

An interesting question raised by the authors is why blocking death results in a fixed number of undead cells, although its activation does not have equally 'precise' effects.

This mechanism had been demonstrated in studies showing that enhanced expression of antiapoptotic Bcl2 family members blocked death receptor-mediated activation of caspase 8 and downstream executioner caspases.