Sentence examples for block cell cycle replication from inspiring English sources

The taxanes are a promising family of anti-tumour drugs that block cell cycle replication by interfering with the microtubule network.

To cope with stalled replication forks, the cell relies on the replication checkpoint to block cell cycle progression, downregulate origin firing, stabilize the fork itself, and restart replication.

DNA checkpoints detect damaged or unreplicated DNA and block cell cycle progress until the damage is repaired or replication is completed, when progress resumes.

UCN-01 also blocks cell cycle progression and promotes apoptosis.

Some viral co-infections can modulate HIV-1 entry in vitro, mainly by modulating chemokines and chemokine receptors [43] [45]; and measles virus has been able to interfere with HIV-1 reverse transcription and replication by blocking cell-cycle progression of CD4+ T lymphocytes [46].

Using a lower moi (0.001 pfu/cell), and removing the compounds before the viral harvest resulted in reduction of viral yields by as much as 98% (Table 6), indicating that the compounds block multiple cycle replication of the virus.

Cellular senescence is considered to be an irreversible block to cell cycle progression in populations of otherwise replication-competent cells (Hayflick & Moorehead, 1961; Narita & Lowe, 2005; Beausejour & Campisi, 2007; Jeyapalan & Sedivy, 2008).

Following irradiation, p53 is activated and induces a crucial block to cell cycle progression providing enough time for sufficient DNA-repair prior to deleterious DNA-replication in S phase.

These had the following functional annotations: cancer, cell cycle, DNA replication, gene expression and cell death.

Both treatments block the cell cycle in G2.

These agents block the cell cycle in G2-M phase.