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Each TMA block can be sectioned and mounted onto glass slides, producing hundreds of nearly-identical slides.
Under ideal circumstances, a single paraffin TMA block can be sectioned into nearly identical glass slides dispensed to many different laboratories.
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Hundreds of pre-invasive lesions can be inserted into a single paraffin block, which can be sectioned and immunostained with a variety of markers [ 71].
The ngTMA blocks can then be sectioned for further staining including IHC, DNA silver ISH (SISH), mRNA ISH, miRNA ISH or a combination of these.
Alternatively, the tissue blocks can be embedded in PEG [ 91] and sectioned with a sliding microtome.
It is imperative that studies be adequately planned so that fresh sections of paraffin blocks can be used as much, and as soon as possible.
Sections from TMA blocks can be used for FISH, allowing gene amplification to be evaluated in hundreds of tumor samples on a single slide.
The blocks can be a choking hazard!
In-between each case-block, a blank-block was sectioned as contamination control.
Each tissue block was sectioned serially.
Blocks were sectioned at 5 microns.
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