Consistent with our model [(Schicker et al., 2011); see also Figure 7A], occupation of the inward-facing conformation with a transported ligand should block the transport-associated current by forcing the transporter into the TIS state (Adams and DeFelice, 2003; Erreger et al., 2008).
The most notable event during the season between the two occurred during the Portuguese Grand Prix, where Senna tried to block Prost from taking the lead by forcing the Frenchman to run close to the pitwall; Prost managed to edge Senna outwards, taking the lead as they went into the first corner but he remained angered by the Brazilian's manoeuvre.
Near the end of the last ice age approximately 15,000 years ago, the Fraser River canyon was blocked by ice, forcing the upper Fraser and Thompson Rivers to drain southward into the Columbia River.
In 1917, Woodrow Wilson, with his wartime legislative agenda blocked by filibusters, forced the Senate to pass Rule XXII, which allowed a two-thirds majority to bring a floor debate to an end with a "cloture" vote.
The display was so impressive that a nearby freeway was blocked by passing vehicles, forcing the authorities to close it for the duration of the concert.
The United States, which does not want the court to have jurisdiction over American soldiers, tried to block the treaty by forcing a vote.
The attackers blocked the road by felling trees, forcing the convoy of vehicles to a halt, according to the Press Trust of India news agency.
With 35 seconds left in regulation, Mitchell was picked off by Ashley Ambrose at the Detroit 35, but Doug Pelfrey, who missed a 35-yard field goal attempt early in the fourth quarter, had a 48-yarder blocked by Ron Rice as time expired, forcing the overtime.
The government did not "suppress dissent," nor has it done so in other elections; or even when the dissenters shut down the oil industry and crippled the economy in 2002-2003 - actions that would have been illegal and blocked by the force of the state in the United States.
Tsonga won a set point by forcing his foe to block a backhand long.
