Sentence examples for block binding of the from inspiring English sources
We further demonstrated that 2C5, but not 1A5, was able to block binding of the RBD to angiotensin-converting enzyme 2 (ACE2), the functional receptor on targeted cells.
The most significant progress is the development of highly potent multivalent ligands that block binding of the toxins to their receptors.
Although the 15D peptide had reduced ability to block binding of the 12G5 antibody, probably because it has a negative Asp residue instead of Arg and it is known that the chemokine binding site of CXCR4 is negatively charged, the infectivity data indicate that the low-affinity interaction of 15D was still sufficient to interfere with viral infection.
Anthracyclines and echinomycin block binding of the HIFs to DNA, leading to diminished expression of HIF-driven genes.
In addition to inhibiting HIV/SIV-CCR5 interactions, CCR5 inhibition would block binding of the chemokine ligands CCL3 5 to CCR5, thereby also dampening inflammatory signaling.
The ability of test sera to block binding of the MAbs to WNV antigen was compared to the blocking ability of control sera from chipmunks without antibodies to flaviviruses.
It is well established that sFas may bind to membrane-bound FasL, thus blocking binding of the ligand to the Fas receptor and preventing apoptosis induction in the target cell.
Antibodies specific for domain 4 of PA are capable of neutralizing toxin by blocking binding of the toxin to host cell surface receptors [10], [32], [33].
The K30A point mutation within the TPR domain of CHIP that blocks CHIP binding to Hsp90 [37] also blocks binding of the isolated TPR domain to the N-terminus of LRRK2 (Supplemental Figure S2C, D).
Aurora A phosphorylation blocks binding of the HURP C-terminus to its own N-terminus, thereby allowing its interaction with microtubules [ 37].
