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The presence of rust could not only block active sites leading to partial loss of activity, but also increase the surface acidity, which would induce side reactions and decrease the selectivity of propylene oxide.
In situations where Eph activation leads to tumour promotion, strategies that block active kinase signalling are sought.
These compounds can adsorb onto the metal surface and block active surface sites, reducing the rate of corrosion.
The results show how surface oxygen bubbles block active catalyst sites and decrease the electrochemically active surface area (ECSA).
In addition, the UPD of Tl and Cu were shown to inhibit THF oxidation, since the deposits probably block active sites on the electrode surface.
However, the recycle catalysts show less activity as compared to the originals, which might be due to photosensitive hydroxide deposition on the photocatalysts surface, and that might block active site of the catalyst (Saeed et al. 2016).
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Binding data was generated for a library of inhibitors based on the ability of each compound to block active-site labeling of the target proteases by a covalent activity based probe (ABP).
Also, increasing steric bulk of the ligand decreases the catalyst activity because of blocking active sites.
The peptide inhibited RSK activation, stimulated apoptosis of HSC and blocked active fibrogenesis, preventing progression and inducing regression of liver fibrosis compared to control mice treated with CCl4.
Seemingly, thiourea adsorbs on the electrode surface blocking active sites.
The bridge-bonded adsorbed formate is stable and suppresses HCOO− oxidation by blocking active site.
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