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Main study limitation is that the trial was not blinded to participants; blinding is impossible to patients in such health educational interventions.
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Blinding was impossible to perform for obvious logistic reasons.
Therefore, the surgeon and patient blinding is impossible owing to the nature of surgical RCT.
Blinding is impossible.
In addition, schools were not randomized and blinding is impossible.
Without a sham surgical control, blinding is impossible.
Since the secondary outcomes are all self-reported, blinding is impossible.
Double blinding is impossible but we felt it is unlikely that the primary outcome we evaluated would be biased by the open design.
Second, how are we to classify, categorize and compare trials of surgical interventions or devices (that is, extracorporeal membrane oxygenation (ECMO) or high-frequency oscillatory ventilation (HFOV)) where true blinding is impossible?
The coders assessing the data will be blind to group assignment; however, the person completing the blood sampling will not be blind as it is impossible to prevent them from knowing participant KMC condition (i.e., skin-to-skin or incubator care).
Although I would love to live in a "color blind" society, it is impossible to live that way when color has been one of the deciding factors of one's fate since the conception of this nation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com