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The lack of blinding in this study could be viewed as a limitation, but blinding patients or clinicians to the treatment allocation was not practical.
It was difficult to control bias and confounders due to the absence of randomization and blinding in this study.
There was no blinding in this study due to the nature of the intervention which may have influenced the outcome assessment.
The lack of blinding in this study could be viewed as a limitation, but we did not consider blinding of patients or clinicians to the treatment allocation practical.
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Therefore, neither therapists nor patients will be blinded in this study.
Subjects could not be blinded in this study to the test conditions, but they were blinded to the hypothesised outcomes.
As all primary and secondary outcomes are participant-reported questionnaires, and participants will be blinded to group allocation, the assessor is also blinded in this study.
Nevertheless, even if the experimenters cannot be blinded in this study, plans should be put into place to blind any analysts involved.
(3) Neither providers nor patients were blinded in this study to the presence of adenoma risk attributes at baseline and this information is likely to have influenced both the provider's management recommendations and the patient's adherence.
After baseline assessments and randomisation, 4 coaches were asked to attend coach education sessions (intervention) and 4 coaches served as controls; therefore, it was not possible to keep coaches blinded in this study.
Although double-blinding in this study would have involved the use of placebo sprays and lozenges at the same time as the active dose, this may have assisted in avoiding bias in patients' perceptions of efficacy.
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