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Thus blinded, sample aliquots were dispensed into a disposable PP plate for dilution.
By spotting these 50 clones together with 26 frequently or rarely involved clones and 62 reference clones, a mini-array was made to estimate the above parameters, and the diagnostic performance of the mini-array was evaluated for an independent set of 30 gastric cancers (blinded – sample set).
Not only blinded sample size adjustment is implemented but also a randomization test is performed.
Internal pilot study, a kind of adaptive design, has gained increased attention for its allowing for sample size adjustment, especially blinded sample size adjustment that do not affect the type I error rate.
We have assessed the CFS disease predictive genes in the original study data and in a new blinded sample set of CFS disease and healthy control samples.
The estimated ICC from the blinded sample size review is also included in the SAP.
Similar(44)
49 known and blinded samples of OPV DNA, representing different OPV species, and two VZV strains were tested.
The report recommends a set of steps to validate the tests, such as repeating the test on blinded samples from a different institution.
The internal quality of genotype data at each genotyping center was assessed by typing 5 10% blinded samples in duplicate or greater, depending on study.
These blinded samples were then sent for analysis.
Thirty-three randomly selected, blinded samples were resequenced for quality control purposes.
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