In a prospective, blinded, randomized, controlled study, Seprafilm was studied for adhesion prevention after the suction and/or curettage evacuation of the uterus in 150 women (Table 1) [75].
We designed this double blinded randomized controlled study to test whether IgM-enriched immunoglobulins administered as rescue treatment in a pneumonia model developing shock, could either limit lung damage and/or contain systemic inflammatory response.
Recently, a double-blind, randomized, controlled study that compared 0.9% saline vs. hydroxyethyl starch (HES 130/0.4) was conducted in penetrating blunt trauma patients who required >3 liters of fluid resuscitation [10].
This single-blind, randomized, controlled study was designed to demonstrate non-inferiority of a primary vaccination course (6 10 14 week schedule) of Tritanrix HB + Hib (first dose) and Quinvaxem (second/third doses) versus three doses of Quinvaxem with respect to the seroprotection/seroconversion rates for all antigens one month after vaccination course completion.
A Phase II, partially-blind randomized controlled study (blind to vaccine, not to schedule), of 19 months duration was conducted in two (2) centres in Ghana between August 2006 and May 2008.
In this phase II, double blind, randomized, controlled study, 280 infants were primed with DTPw-HBV/Hib-MenAC or DTPw-HBV/Hib vaccines at 6, 10 and 14 weeks of age.
The COOLS trial is a multicentre, double blind, randomized controlled study, comparing FV- guided surgery (experimental arm) to conventional white light (WL -guided surgery (control arm).
Strengths of the present study include the assessor-blind randomized controlled study design and the simple assessment protocol requiring no tools or technical equipment [ 18].
