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But in adjuvant settings, control arms do not usually use placebo or blinded procedures, but observation only.
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Data obtained by non-blinded and the blinded procedure significantly correlated (overall R=0.780. p<0.0000001).
A blinded procedure was adopted with masked goniometers and a second assessor present to record the measurement.
All samples were analysed following a blinded procedure.
Brain tissue was sectioned, hematoxylin and eosin stained (H&E) and analyzed in a blinded procedure by a neuropathologist (TO) for presence and grade of tumors.
F3 generational male and female Sprague-Dawley rats from control and vinclozolin lineages were used in a blinded procedure for the behavioral studies.
By using a blinded procedure, we could avoid the usual bias inherent in retrospective evaluation.
21 days later, the animals were enrolled into the final blinded procedure as followed.
The measurements were performed by 2 dentists in a blinded procedure.
Each of the joints was examined by a blinded procedure and classified for the severity of the joint lesions.
CD138 immunoreactivity was scored by two independent observers in a blinded procedure without prior knowledge of the clinical information and was classified for the staining of the tumor or the stromal cells, in either the tumor or the stroma, as 0 (less than 5% of cells); 1+ (5% – 25% of cells); 2+ (25% – 75% of cells), or 3+ (more than 75% of cells).
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