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The data are presented as the average of at least three blinded experiments performed on different days.
Our methods have been tested against industry-leading technologies in two blinded experiments based on Coriell DNA samples and SNP genotype data from the International HapMap Project.
Beating rate was estimated by counting the number of beats per min in five different cell clusters in five independently blinded experiments.
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"So it was really a blinded experiment, because I didn't know what was what".
In a "blinded" experiment, many such slices (>30/group) were examined, and the distances between adjacent gold beads were measured along the contour of the cell membrane.
In this assay, the tubes in each field were measured by three individuals in a blinded experiment and the total tube length averaged and plotted for each data set (Fig. 6ii).
The CSF samples were handled according to the same protocol for quantitative MALDI-FT-ICR MS measurements we reported previously [12], which consists of a blinded experiment in which the samples were digested by trypsin and subsequently measured by MALDI-FT-ICR (APEX IV Qe 9.6 Tesla MALDI-FT-ICR mass spectrometer (Bruker Daltonics, USA)).
More than 1000 granule neurons and approximately 50 motor neurons were examined in a blinded experiment.
Approximately 50 cerebellar Purkinje neurons were examined in a blinded experiment, from a minimum of three C9ORF72-ALS cases.
A total of 9 mice per inoculum, corresponding to 3 animals per genotype, were analyzed in a blinded experiment design.
To this end, we designed a small blinded experiment to test the predictive power of the four CLS biomarkers (LEU3, ADD66, FYV6, and CWP2).
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