In [28], Wang et al. utilize a blind variable-diagonal loading (VDL) multiuser detector, based on the concept of optimizing the worst-case performance over properly chosen bounded uncertainty sets that are determined by a bounding probability, to provide further robustness against small-to-medium prior signal modeling errors in MC-CDMA systems.
All studies incorporated double-blind, variable-expected duration placebo lead-in periods to blind patients and investigators to the start of active therapy.
In the absence of a double-blind, subjective variables such as pain assessment could be considerably influenced by the enthusiasm for a novel technique.
The model is applied to the variable blind DGU, varying the angle of rotation of the blind.
All MIPS ratings were performed blind to other variables.
34 In the past LA trials have shown methodological limitations including small sample size, variable blinding and crossover designs.
Expression patterns were independently determined by two investigators in a semiquantitative manner by light microscopy considering whole tumour specimen slides blind to clinicopathological variables and outcome, respectively.
In a double-blind placebo controlled variable dose RCT trial of MPH (5 20 mg/day over 7 days) for advanced cancer-related fatigue, the mean baseline FACIT-F score was 17.0 (standard deviation (SD) = 7.9) and mean change in FACIT-F score from baseline for placebo was 7.5 (SD = 11.3) [ 22].
The duration of the double-blind phase was variable, and would continue until the patient experienced a recurrence (defined as hospitalization, specified increase in PANSS, specified dangerous behavior, or specified worsening on the Clinical Global Impressions Severity of Illness scale), or until study termination.
Cell counts were performed blind to the temperature variable.
To evaluate villus height, crypt depth, and muscular layer and intestinal wall thickness (from the villus apex to the mesothelium of the tunica serosa), 40 measurements per animal were randomly made by a blind observer for each variable in each segment using Image Pro Plus 4.5 image analysis software (Media Cybernetics, Silver Spring, MD, USA).
