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Alcohol seems to have been used as a narcotic during operations, and bleeding was stopped by hot oils and tar.
The skin and periosteum of the skull were incised and reflected, and bleeding was stopped by bipolar electrocoagulation.
After removal of the collecting tube, bleeding was stopped by applying gentle pressure to the puncture site using sterile cotton.
Phase III was the definitive resuscitation period; after bleeding was stopped by full ligation of the splenic artery and vein, rats received whole blood and lactated Ringer's solution at a ratio of 1 2 to maintain the MAP at 80 to 90 mmHg for 2 hours.
Five hundred and seventy-six SD rats of different age and sex - 6 weeks (male, n = 96; female, n = 96), 14 weeks (male, n = 96; female, n = 96) or 1.5 years (male, n = 96; female, n = 96) - were divided randomly into six groups before bleeding was stopped: no treatment group, and 40-mmHg, 50-mmHg, 60-mmHg, 70-mmHg and 80-mmHg target MAP groups (n = 16/group).
The bleeding was stopped.
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Make sure the bleeding is stopped to decrease the amount of blood loss that occurs and help the wound begin healing.
The heparin dose was adapted at least once daily, according the aPTT value and clinical tolerance; it was stopped when bleeding occurred and restarted after bleeding was controlled.
rFVIIa was given only after all other options, including revision, to stop bleeding was failed.
Once injury has occurred, however, we are convinced that the best way to break the feedback loop – the 'bloody vicious cycle' of bleeding and resuscitation, resulting in coagulopathy, acidosis and hypothermia, leading to more bleeding – is to stop bleeding early.
Super selective catheterisation and embolisation with coils (f) allowed the bleeding to be stopped.
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