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Suspicion of bleeding is based on melena or hematemesis or a progressive decrease of the hematocritus.
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Classification of bleeding was based on previous reports and suggested recommendations.
The definition of death of bleeding was based on death within 30 days after discharge, since it is difficult to assess if death actually results from bleeding.
Second, our measure of VTE events and bleeding are based on administrative data and are dependent on appropriate documentation and coding.
Hysterectomy and procedures to control bleeding were based on the Canadian Classification of Health Interventions (CCI), which was used from April 1st, 2001 onwards.
50 Both these studies showed that the risk of bleeding was based on three factors: severity of liver disease as measured by Child class, variceal size and red wale markings.
The probability of experiencing bleeding was based on clinical trial data: patients who had a platelet count ≥50 × 10/L were assumed to have a 12.64 % per-cycle probability of an outpatient bleed (i.e. not requiring hospitalization) and a 0.30 % per-cycle probability of an inpatient bleed (requiring hospitalization) [ 21].
Indication for reoperation because of suspected surgical bleeding was based on evaluation of clinical and hemodynamic changes.
The death rate from causes other than procedures for heavy menstrual bleeding was based on values for women in the government actuary's department life tables of England and Wales for the years 1998-2008.
Knowledge is based on forgetting.
26 Costs for management of minor bleeds were based on the NICE clinical guideline for AF. 25 Acute management costs for all other events (IS, ICH and HS) were calculated from a recent study of AF patient data from a UK stroke registry, as were costs for long-term management of disability resulting from IS, ICH or HS.
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