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For example, after ACL reconstruction there is an acute post-surgical haemarthrosis with bleeding from the bone tunnels.
We have paid special attention to the clinical fact that the fibrocartilage tissue can be regenerated in an osteochondral defect by creating many small holes penetrating into the subchondral bone at the bottom of the defect space in order to enhance bleeding from the bone marrow [ 12].
We paid attention to the fact that sufficient fibrocartilage tissue can be regenerated in an osteochondral defect by creating many thin holes that penetrate the subchondral bone at the base of the defect in order to create bleeding from the bone marrow and subsequent clot formation ("Microfracture" technique).
One intraoperative heavy bleeding from the bone occurred in one patient who made use of antiplatelet agents in the DHS MIO group.
In addition, it is generally accepted that the majority of the growth factors most likely remain in the scaffold until the bleeding from the bone has ceased.
At 2 weeks, the defect treated with the DN-gel implantation was filled with a blood clot, which was formed by spontaneous bleeding from the bone marrow after surgery.
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The sclerotic bone inside each bone fragment was refreshed and bleeding from the refreshed bone surfaces confirmed.
With the patient under lumber spinal anesthesia, the surface of the cartilage legion was arthroscopically scratched with curettage for débridement, but bleeding from the subchondral bone was avoided.
Apart from self-limited cancellous bone bleeding from the iliac wing fracture, pan-CT and pelvic angiography ruled out intrathoracic, abdominal, and pelvic source of bleeding.
Surgical treatment consisted of osteotomy until healthy bone with bleeding from the surfaces was visible.
Any bleeding from the skull during the craniotomy was controlled with bone wax.
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