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Figure 2 Distribution of probability of bleeding based on the two most informative sequential patterns of shape of the ABP waveform.
Similar results applied to the subgroup analysis of gum bleeding based on the retrospective and prospective studies (data not shown).
Since upper GI bleeding is a non-specific diagnosis which can be due to oesophagitis, varices, and malignancy in addition to gastroduodenal ulcer, we defined ulcer bleeding based on the endoscopy reports which are computerized in all HA hospitals.
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Sample size was also calculated on the outcome measure oral health status using the assumption that 50% of pregnant women in the control group will have gingival bleeding (based on trials in this area) [ 21].
Thus, we have to manage and treat massive bleeding based on our own clinical decision.
These results do not correspond to the findings of the prospective study by Nielsen et al., in which thrombolysis and the use of an endovascular device were associated with an increased risk of bleeding based on univariate analysis [ 19].
Furthermore, the ARISTOTLE trial showed similar results with a reduced dosing regimen of apixaban in patients at particular risk of bleeding (based on age, weight, and serum creatinine, as noted above).
For both the all-patient and OAC-naïve patient cohorts, pre-index HF and higher risk of bleeding (based on ATRIA score) were associated with lower adjusted odds of dabigatran use.
Patients considered to be at particularly high risk for bleeding, based on platelet count (Plts) and international normalised ratio (INR) received transfusions of platelets and/or fresh frozen plasma prior to the procedure.
Bleeding during TTM was more frequently observed in patients receiving an invasive intervention, such as IABP, extracorporeal membrane oxygenation (ECMO), and cardiogenic shock, whereas thrombolysis and the use of an endovascular device, coronary angiography, or percutaneous coronary intervention (PCI) were not associated with an increased risk of bleeding based on univariate analysis.
In their study, the investigators initially identified cases with a diagnosis of upper gastrointestinal (UGI) bleed based on International Classification of Primary Care Code or free text related to UGI bleed, which was screened via natural language processing.
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