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It was common practice to assess the effect of estrogen therapy on endometrial cancer only among women presenting with uterine bleeding, as a marker of estrogen use and cancer.
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In this group, treatment with rFVIIa significantly reduced the need for all blood products, surrogate markers of bleeding, as well as potential donor exposure as compared with placebo during standard-of-care management of hemorrhage (Table 4).
Analyses incorporating risk of bleeding as a continuous variable (fig 1 ) suggested a greater absolute decrease in bleeding rate as bleeding risk increased.
We used further bleeding as an outcome.
Unilateral nipple bleeding as the first significant bleeding manifestation has not been reported in a coagulation disorder before.
A common minor mismatch was the coding of lower GI bleeding as GIBLEED (unspecified GI bleed, three subjects) and SGIBLEE (surgery for GI bleed, one subject).
Whether thrombocytopenia was directly involved in bleeding through the nadir platelet count or indirectly as a marker of severity remains unclear.
Compared with nontransfused patients, transfused patients were also more likely to experience HAP (OR = 1.63, 95% CI = 1.38 to 1.93) or BSI (OR = 2.90, 95% CI = 2.53 to 3.34; P < 0.0001 for each) and to have undergone a procedure serving as a marker of high bleeding risk (P < 0.0001 for all five procedures).
It isn't as much of a marker for success as it used to be.
To assess the value of endometrial thickness as a marker of endometrial abnormality risk during hormone therapy (HT) and to study the correlation between abnormal bleeding and abnormal endometrial histology in patients with thick endometrium.
Humanity views ownership as a marker of status.
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