Sentence examples for bleeding activation from inspiring English sources
20 In patients with traumatic bleeding, activation of plasmin occurs and plays a key role in the fibrinolytic response in the early hours after injury.
Extracorporeal circulation during cardiac surgery induces haemostatic alterations that lead to an inflammatory response (IR) and postoperative bleeding secondary to activation of the coagulation-fibrinolytic cascades.
The venovenous and venoarterial application of extracorporeal membrane oxygenation is often associated with coagulation and bleeding complications, with activation of the inflammatory cascade, with damage of red blood cells and with technical problems [ 12- 14].
In addition, SLVVIQ stopped alkali-induced gill bleeding and mimicked trypsin activation (Figure 7).
In parallel to caspase-3 activation also bleeding signs decreased after IVIg therapy.
The demonstrated safety of rFVIIa is probably due to its localization to injured areas of the vascular tree by binding to tissue factor (TF) and activated platelets at the bleeding site, thus avoiding systemic activation of coagulation.
Rare mutations in the P2Y12 gene that disrupt P2Y12 receptor function result in compromised ADP-induced platelet activation and increased bleeding times [1], [7], [8].
Certain studies have reported thrombin inhibition via PAR-1-mediated platelet activation without increasing bleeding in preclinical models and small-scale clinical trials [ 79, 80].
11 Disorders of haemostasis are often associated with prostate surgery, with the risk of bleeding being related to systemic and local activation of fibrinolysis.
Severe bleeding episodes may also result from the activation of the fibrinolytic system which predominates in metastatic prostate cancer, pancreatic adenocarcinoma or APL [ 3, 4, 14, 15].
Complications include coagulation disorders (bleeding diathesis, hyperfibrinolysis) from platelet defects and plasmin activation, as well as pulmonary dysfunction from neutrophil sequestration and degranulation.
