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Open image in new window Fig. 9 A 64-year-old patient with rising PSA and history of recurrent urothelial cell carcinoma of the urinary bladder treated with intra-vesical BCG therapy.
Among patients with transitional cell carcinoma of the bladder treated with cystectomy, high tumoral expression of ERCC1 correlated with longer survival in patients without adjuvant chemotherapy and was associated with shorter survival in those with adjuvant chemotherapy.
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Pathological changes of blood vessels have been reported in urinary bladders treated with radiation in mice [ 7– 9], suggesting the potential role of endothelial dysfunction in the pathogenesis of RIBI.
Open image in new window Fig. 14 Acute uncomplicated urethritis in a 30-year-old man with neurogenic bladder treated by intermittent self-catheterisation. Physical examination revealed induration and tenderness of the corpus spongiosum and purulent urethral secretions.
In the present study, a significant decrease in expression of TM was observed in the bladder tissue treated with radiation at the delayed phase, suggesting the possible association between endothelial dysfunction and bladder fibrosis.
The recurrence rate for superficial bladder tumors treated with complete resection averages 88%.
Therefore, LN metastasis (LN status), and the number of involved LNs (LN burden) determine the outcome of patients with bladder cancer treated with cystectomy [ 8].
In a pilot study, it was found that 20percentt of dogs with bladder tumours treated with piroxicam alone had a partial or complete response [ 41].
We profiled the expression of 671 miRNAs in formalin fixed paraffin embedded tumors from patients with advanced bladder cancer treated with cisplatin based chemotherapy.
Iyer et al. [31] recently investigated the genetic basis of remission of a patient with metastatic bladder cancer treated with RAD001 using whole-genome sequencing.
High levels of nuclear and cytoplasmic TFAP2α protein were a predictor of increased overall survival and progression free survival in patients with advanced bladder cancer treated with cisplatin based chemotherapy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com