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The present study follows up on earlier results that showed that several genes related to structural protein synthesis, smooth muscle hypertrophy, and hyperplasia were up-regulated significantly in rat bladder tissue as a result of SCI [10].
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Conditions with lack of bladder tissue as well as low compliance and high pressure bladders, often need surgical intervention with an abdominal conduit for self-catheterization and/or a bladder augmenting approach, to reduce the risk of secondary renal failure.
Animal experiments with chemotoxic and mechanic stress to astroglia [ 20, 52, 53] and urinary bladder tissue as well as studies with isolated connective tissue such as fibroblasts and cartilage [ 54– 56] have revealed that tissue injury and inflammation with subsequent healing is associated with a specific physiological process that involves the local production of estrogen from its precursors.
The DLK1 promoter was partly methylated in benign kidney and bladder tissues as well as in leukocytes.
Vitamin D treatment per se did not increase cathelicidin mRNA or protein in bladder tissue, as determined by quantitative RT-PCR and microscopy, respectively (data not shown).
The aim of this study was to produce a natural, acellular matrix from porcine bladder tissue for use as a scaffold in developing a tissue-engineered bladder replacement.
Remarkably, the expression of the HOTAIR- EZH2 target genes could efficiently discriminate between recurrent and non-recurrent tumors, as well as non-tumor bladder tissue in an unsupervised manner (Fig. 2c).
In this study we compared the regeneration of bladder tissue with a collagen-based biomatrix in a sheep model for bladder exstrophy with bladder tissue regeneration in normal bladder.
Rodriguez used pig bladder tissue to create a mold of Halpern's missing finger and attached it to the stump.
The imaging technology could be utilized in the future to provide urologists with an immediate impression of extracted bladder tissue, or as part of a cystoscopic device to evaluate the bladder in real time.
Bladder tissue engineering appears as an appealing alternative through development of biological substitutes, which could restore structural and functional aspects of damaged tissues and organs.
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