These compounds were tested on cell lines obtained from bladder tumors of various stages [superficial (pTa and pT1) vs. invasive (⩾pT2)].
To investigate miRNAs potentially involved in invasion, we profiled the expression of miRNAs and mRNAs in bladder tumours of various stages and grades.
To study the possibility of an autocrine growth mechanism in bladder carcinoma, we investigated the ability of various bladder carcinoma cell lines to proliferate in serum-free medium.
To find the role of telomerase and sFas in the pathogenesis of various bladder lesions associated with schistosomiasis and to correlate the results with clinicopathological parameters.
Expression array data of various bladder cancer stages were obtained from NCBI GEO (GDS1479), and average±S.D. was calculated.
The collagen deposition in bladder occurs frequently during development of various pathological processes and eventually cumulates in bladder fibrosis, and finally induces a flaccid bladder.
We first screened human cancer cell lines of various origins: bladder (MGH and USB), cervix (HeLa), prostate (PC3) and breast (T47D and MCF7) for CSB protein expression.
The observed differences in the susceptibility of various human bladder cancer cells to Ad5WS1-induced cytolysis could be attributable to various levels of cell infectability by adenovirus among different cell lines.
Future studies that seek to further delineate the relationship and, thus, pathogenesis of various forms of bladder cancer will provide additional insight into the development of bladder cancer.
Several studies have focused on construction of microarray based classifiers for prediction of various aspects of bladder cancer like stage [ 7, 8, 11, 17, 18], progression [ 7, 8, 19], recurrence [ 7], survival [ 18, 20], and treatment response [ 21].
