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The exact contribution of nerve growth factor (NGF) to bladder function is not known but a correlation between bladder overactivity and elevated urinary bladder NGF has been suggested.
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More importantly, bladder function was not restored in either group [ 60].
The pathways that mediate the central circadian control over bladder function are not clear.
In this pilot telemetric study, bladder function was not affected by oral administration of urological drugs at their recommended clinical dosages.
Their function is not known.
Bladder function is complex, with parasympathetic control of bladder contraction and sympathetic and voluntary control of the bladder neck and sphincter.
Hence, the normal circadian control of bladder function is lost.
All rats received manual bladder expression three times a day until bladder function was reestablished.
Bladder function was assessed by urodynamics at 2 and 14 days following SCI.
On the fifth postoperative day, the bladder function was tested and urinary retention measured.
Animals' bladders were manually expressed twice daily until control of bladder function was completely regained.
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