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Nicholas died in the bitter knowledge of general failure.
The women who have no illusions about love may be lonely, but their bitter knowledge gives them strength.
The most damning element here is not that George Zimmerman was found not guilty: it's the bitter knowledge that Trayvon Martin was found guilty.
The bitter knowledge that no matter how much you admire a work of art, your comments always sound as if you had trouble with your speech centres.
So she settles back down to imagine where they will go out to play on this gorgeous day while she sits alone with her precious, bitter knowledge.
Similarly when Barton surprised her half-naked, Janney silently showed us Margaret's longing for her husband's touch and, simultaneously, her bitter knowledge that her marriage could be faked no more.
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It is a perfect Yatesian sentiment, self-deception yielding to an explosion of bitter self-knowledge.
The loneliness can be made all the more bitter by the knowledge that it wasn't always this way.
And as he lost yet another debate (I'll discuss the post-debate polls later) mainly because of his anger and tone, I couldn't help thinking that what made McCain so bitter was his knowledge that he was, in fact, President Bush, at least in his policies and voting record.
Additional mutations on the putative G-protein binding region emerging from the model and in the helices involved in gating (especially helix TM7) are desirable to complement our knowledge on bitter taste receptor activation mechanism.
There are many handbook and website sources including knowledge about bitter melon.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com