No difficulty at all A little bit of difficulty A moderate amount of difficulty A great deal of difficulty I cannot do these activities In the last 4 weeks, how much difficulty have you had caring for yourself, such as eating, bathing or showering, dressing, and getting around?
No difficulty at all A little bit of difficulty A moderate amount of difficulty A great deal of difficulty I cannot do these activities Do you currently have someone available who would take care of you if you wanted and needed help?
There's a bit of a linguistic difficulty in writing a book on junk DNA, because it is a constantly shifting term.
We are hit with the first (and biggest) such problem, at the very beginning, in a brief "Notes on Nomenclature": There's a bit of a linguistic difficulty in writing a book on junk DNA, because it is a constantly shifting term.
Scoring is on a 4-point scale with responses spanning 0=no difficulty, 1=a little difficulty, 2=quite a bit of difficulty and 3=very much difficulty.
Total scores can range from 0 to 80. Function is defined as follows: extreme difficulty or unable to perform activity (0 19 points), quite a bit of difficulty (20 39 points), moderate difficulty (40 59 points), a little bit of difficulty (60 79 points), and no difficulty (80 points).
The LEFS consists of a 20 item measure of daily activities and function based on a five-point Likert scale [ 35], where difficulty levels for each item are classified into: extreme difficulty or inability to perform activity (0 point), quite a bit of difficulty (1 point), moderate difficulty (2 points), a little bit of difficulty (3 points), and no difficulty (4 points).
Two-thirds of patients (126 out of 183) rated at least one item at '2 – quite a bit of difficulty' or '3 – very much difficulty'.
The St Paul's/Occupy thing was not just a little bit of local difficulty.
In the RCT by Kaufman et al, the proportion of patients taking on-demand dapoxetine 60 mg who reported "not at all" or "a little bit" of interpersonal difficulty related to ejaculation increased from 40.9% at baseline to 76.8% at the 9-week study endpoint, compared with 43.0% to 64.2% for those taking placebo.
