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1. To determine the survival and morbidity of infants at discharge with a birthweight of less than 1500 g in the geographically defined population of East Anglia.
Conclusion: Our study showed that gestational age, blood transfusion volume and iron load by transfusions are associated with the risk of occurrence of ROP in infants with a birthweight of less than 1250 g.
Births with a birthweight of less than 500 g were excluded from the analyses.
Babies with a birthweight of less than 1000 g who have a UAC in situ in an acceptable position.
In addition to standard intravenous nutrition, 430 babies with a birthweight of less than 1000 g who have an umbilical arterial line in situ will be randomised in 1 1 ratio to receive either an amino acid solution (TrophAmine®) or placebo (saline) administered through the umbilical arterial catheter for the first 5 days.
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Low birthweight, defined as births of less than <2500 g, has been widely used as a convenient measure of an adverse birth outcome.
Low birthweight (LBW) (weight at birth of less than 2500 g) is associated with greatly increased risk of mortality and morbidity in infants (1).
Of the children with a birthweight of 1500 g or less, 50% died during the first 6 months.
on behalf of the COhorts Group Associations between parental and offspring size at birth are well established, but the relative importance of parental growth at different ages as predictors of offspring birthweight is less certain.
Infants also benefited from combined interventions; they were less likely to be born of low birthweight and less likely to die during pregnancy or during the first seven days of life.
The influence of sex on birthweight is less significant than the influence of sex combination, as reported by Corney et al [ 17].
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