Whilst birthweight, growth and adult blood pressure were unaltered, reduced activity in an open-field behaviour test, increased fat pad:body weight ratio and increased body mass index were observed in male, but not female, offspring.
While we demonstrate that common genetic variation in IGF1 modestly influences circulating IGF-1 concentrations at birth and during childhood, we did not find a major contribution of IGF1 to birthweight, growth or response to oral glucose.
Specifically, we assess the relative importance of parental birthweight and growth during different growth intervals from birth to adulthood as predictors of offspring birthweight in four cohorts from low and middle income countries (LMICs).
Maternal and paternal birthweight and growth from birth to 2 year each predict offspring birthweight.
However, these variants are not associated with birthweight, childhood growth and insulin secretion or action.
A search of the literature was conducted on three databases (Pub Med, the Cochrane Library, EMBASE from 1980 to June 2002) using the subject headings: infant, (premature, very low birthweight), anthropometry, growth, birthweight, head, cephalometry, gestational age, newborn, and reference values.
There is some evidence that air pollution is associated with lower birthweight and growth restrictions [ 30, 31] also shown previously in one of the cohorts of the present study [ 32] which are known risk factors for type 2 diabetes mellitus [ 33].
To our knowledge, there have been no previous animal studies carried out to investigate the effect of short duration high glycaemic intakes in the third trimester of pregnancy and its effects on offspring birthweight and growth rates.
In this study, we have now demonstrated that short duration, high glycaemic intake during late gestation that causes transient elevations in glucose and insulin concentrations, compared to the control ewes, had substantial effects to increase offspring birthweight and postnatal growth rates.
We sought to evaluate the association between placental histological abnormalities and birthweight discordance and growth restriction in twin pregnancies.
The aim of this study was to determine the optimal ultrasound formula for prediction of birthweight and fetal growth restriction (FGR) in gastroschisis.
