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The median age at presentation was 1 day and median birthweight was +2.21 SD score (SDS).
Women should consider giving up coffee in pregnancy, according to a scientist whose study found that drinking even a single mug a day appeared to reduce baby birthweights.
In our study, paternal smoking amount played an important role on the infant birthweight, especially fathers who smoked >20 cigarettes per day.
Compared with those born to non-smoking mothers, the birthweight notably decreased with advancing number of cigarettes smoked per day: being doubled OR with statistically significance of LBW.
Assuming a confidence level of 95%and80%0% power, and with an expected infant mortality between day 2 and 12 months of age of 25% among low birthweight infants, we would need 720 low birthweight infants in each of the vitamin A and placebo groups to detect a 25% reduction in mortality associated with vitamin A supplementation.
The patient was an extremely-low-birthweight (ELBW) male infant, who had been transferred the previous day from the NICU of another hospital in Palermo, Italy, where he was born on February 19.
Perinatal outcomes were: Apgar score <7 at 5 minutes, admission to neonatal intensive care unit (NICU), stillbirth (neonate showing no signs of life at time of delivery), low birthweight (birthweight <2500 g) and early neonatal mortality (ENM) by discharge or day 7. Deaths occurring in the first week of life after discharge (at home or during a postpartum readmission) were not captured.
A child that was expected to be born with the average birthweight of 3.6kg lost 21-28g for every 100mg of caffeine the mother consumed each day, the scientists say in the journal BMC Medicine.
Maternal and neonatal characteristics are presented in table 1. Women with pre-eclampsia were less likely to deliver by day than at night, OR 0.29 (95% CI 0.09 to 0.91) and low birthweight babies (<2.5 kg) were more likely to deliver by day, OR 5.58 (95% CI 1.23 to 25.38).
Our value of 151 g compares well with previous studies demonstrating that newborns of nonsmoking mothers whose fathers smoked >20 cigarettes per day had a mean deficit of 88 g [ 37] and an average reduction in birthweight of 120 g [ 38].
Compared with records that linked to NICUS, those that did not link were significantly (p < 0.0001) more likely to include babies who: died on the day of birth (11% vs 2%) were born at ≥ 32 weeks gestation (26% vs 11%), birthweight ≥ 1500 g (38% vs 25%) or transferred to another perinatal centre (36% vs 0.2%).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com