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For each birth by a woman with breast cancer, 50 comparison births matched by month and year of birth, by county of mother's residence, and born to 50 different women, who were not diagnosed with any cancer before or during the pregnancy or until 2 years after the birth were selected from the Birth Registry.
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For each case child with interview data, a 'control list' of six children, matched for sex and date of birth, was selected from the birth register of the local authority area in which the case child died.
The result of this selection was that although births were selected from all the CWSs included in the study, the number of births from each CWS varied greatly, with most records coming from Ft. Wayne.
Factors that could confound the relationship between PAH exposure and anthropometric parameters at birth were selected a priori from a set of characteristics and were tested in a multivariable regression analysis (Table 1).
Altogether, 33 443 single births were selected for the comparison cohort.
Therefore, in order to back-reference to month and year of birth, we assumed the month of routine school entry as examination date (August 2009), since many kindergarten places become available in this month, and subtracted age at KEE. Month-of-birth cohorts were selected from ASHIP data that reached the respective age at KEE in August 2009.
For each case, eight controls matched on birth year and sex were selected from the total Danish population using the Civil Registration System (Pedersen, 2011) and risk-set sampling (Rothman et al, 2008).
Histologically confirmed breast cancer cases (n = 1,011) and controls (n = 1,011) with no present or previous history of cancer, matched on year of birth and menopausal status, were selected from several teaching hospitals and community in Seoul during 1995 2003.
For each case, eight controls matched on birth year and sex were selected from the total Danish population through the Civil Registration System (Pedersen, 2011) using risk-set sampling (Rothman et al, 2008); that is, the controls had to be alive and at risk for a first diagnosis of cancer (except nonmelanoma skin cancer) at the time the corresponding case was diagnosed (index date).
Unmatched liveborn controls from the same geographical region and time period were selected from birth certificates or birth hospital records.
Low birth weight and control groups were selected from the eligible cohort, according to birth weight percentile cut points [ 29].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com