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To assess whether the mortality and morbidity risks vary with birth weight standard deviation score (BWSDS) in growth restricted extremely preterm infants.
We calculated birth weight standard deviation scores according to Finnish birth weight standards, which are based on 75,061 singletons born in 1979 1983 in Finland (19).
As described before, the birth weights analyzed were corrected for gestational age and the sex of the child by using the birth weight standard deviation (SD) score.
There was a significant association of infants GHR isoforms with placental weight (P < 0·001) and birth weight standard deviation scores (P = 0·04) with the fl/fl genotype associated with a larger placental and birth weight.
Birth weight standard deviation score (z-score) and the prevalence of large- and small-for-gestational-age infants (i.e. infant birth weight >90th or < 10th centile, adjusted for sex and gestational age 22) were also recorded.
Both measures were lower in preterm infants of lower birth weight standard deviation scores and smaller occipitofrontal circumference at time of scan, whereas CSA alone was lower in association with smaller occipitofrontal circumference at birth.
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Further, those lost to follow-up due to lack of parent rated ADHD symptoms did not differ from the participants in the current study in gestational age/preterm status or in birth weight standard deviations [SD]/SGA status (P-values > 0.13).
Nevertheless, that early growth pattern is important is also supported by our finding that the change in weight standard deviation score from birth to term was not related to REE or REE/LBM ratio, although a higher weight attained at 40 postmenstrual weeks (term) was related to higher REE through its association with LBM.
These were used to calculate weight standard deviation scores (weight SDS) for birth and 3 months, using 1990 UK reference data (Cole, 2009; Freeman et al., 1995).
Of note, the baby's weight standard deviation score had decreased from −2.17 at birth to −2.66.
AF = amniotic fluid; FHR = fetal heart rate; * p < 0.05, ** p < 0.01, *** p < 0.001 The mean birth weight (± standard deviation) of newborns was 3503 ± 617 g in the women with 6 18 antenatal visits, 3014 ± 1033 g in the non-attenders and 2704 ± 1156 g in the under-attenders.
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