Despite basing our candidates on preterm birth pathways [18], we analyzed genes according KEGG biological pathway and found several interesting associations, including a result that stood up to a Bonferroni correction.
Τhis illustrates that beyond the role of PRLR signaling in adaptive thermogenesis at birth, this pathway may also affect later, white adipose tissue development and metabolism.
In secondary analyses, we controlled for some factors potentially on the causal pathway (birth weight, gestational age, abnormal reflexes) and re-ran models excluding low birth weight and preterm infants.
They can then serve as a useful tool for researchers to learn more about the basic pathophysiology of preterm birth and the pathways leading to preterm labor.
Periodontal disease has been associated with preterm birth, but the biological pathway for this association is not known.
All midwives on the Birth Centre used the pathway to inform care of a woman during her labour and birth as it was the only documentation in use.
According to this model, paracetamol is mostly metabolized by sulphation in neonates and infants, which is an efficient elimination pathway at birth [ 5].
Otx2 is strikingly restricted to relay centers in the primary visual pathway at birth before PV-cells are evident [ 31], including the retina, LGN, and visual cortex (V1).
As a supplementary analysis, we examined the role of birth weight on the pathway between maternal glucose or obesity and offspring obesity.
