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a Factors adjusted for include: paternal age, parental education, place of child's birth (Kingston parish vs. other parishes), consumption of root vegetables ("yam, sweet potato, or dasheen"), "cabbage", salt water fish, and cakes/buns.
Additionally, because a disproportionate number of our controls were drawn from the Kingston area and parental education level is a known factor associated with ASD, place of child's birth (Kingston parish vs. other parishes) and parental education level were considered as a priori potential confounders in our multivariable model.
In our final multivariable GLM analysis, we compared mean BMC of ASD cases and TD controls after adjusting for paternal age, parental education, place of child's birth (Kingston parish vs. other parishes), consumption of root vegetables ("yam, sweet potato, or dasheen"), "cabbage", salt water fish, and cakes/buns.
*Standard deviation (SD) for adjusted model equals square root of means squared error in the final multivariable GLM. a Factors adjusted for include: paternal age, parental education, place of child's birth (Kingston parish vs. other parishes), consumption of root vegetables ("yam, sweet potato, or dasheen"), "cabbage", salt water fish, and cakes/buns.
The latter included the relationships between paternal occupation at birth and parish of residence at birth, and between parish of residence at birth and CVD.
In a multivariable GLM adjusting for paternal age, parental education, place of child's birth (Kingston parish), consumption of root vegetables, cabbage, saltwater fish, and cakes/buns, there was still no significant association between BMC and ASD status, (11.5 μg/L for cases vs. 11.9 μg/L for controls; P = 0.48).
I told him (as was true) that my great-grandfather, Patrick, was a stonemason in Bantry, County Cork, like his father and grandfather before him — I'd seen their illiterate Xs on parish birth certificates — and their names were Sullivan, not O'Sullivan, and if they weren't Irish, I don't know who — "I don't know about any of that," he said.
GLMMs controlled for study parish, birth cohort, and an effect of twin deliveries as fixed effects and maternal family line as a random effect.
The TPR includes data on name, place of residence, sex, age, civil status, place of birth (country, county, parish), citizenship, immigration (date, country, ground for settlement), and relations (married couples, child parent).
All the above analyses controlled for study parish and birth cohort.
Study parish and birth cohort were included into the model to take spatial and temporal variation in female survival rates into account.
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Justyna Jupowicz-Kozak
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