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Appropriateness of fetal growth is then expressed as the ratio of the observed birth dimension to the estimated optimal birth dimension for a neonate with the same values for non-pathological determinants of fetal growth.
This method is based on three underlying concepts: 1. Appropriateness of growth can be expressed as the ratio of the observed birth dimension to the optimal birth dimension for that an individual neonate.
The variation between these proportions may result from variation in the accuracy with which each birth dimension can be measured.
In contrast to percentile position, there is little literature describing the clinical associations of appropriateness of growth expressed as proportions of a desirable birth dimension [ 21].
In this method, appropriateness of intrauterine growth is expressed as the ratio of the observed birth dimension to the optimal birth dimension rather than as being above or below a specified percentile position of the population distribution of that dimension, avoiding the problems inherent in the use of percentile position.
The method reported in this paper introduces two innovations, (i) using optimal, rather than expected, growth as the standard, and (ii) reporting the ratio of the observed to optimal birth dimension as the indicator of appropriateness of growth, rather than a percentile position.
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Assessing appropriateness of growth then requires values for the optimal birth dimensions for the neonate in question.
Since the primary determinant of birth dimensions is the duration of growth, reliable estimates of gestational duration (GA) are essential, yet exclusion criteria for poor quality gestational data are likely to exclude a biased sample.
The most precise percentile estimates are those at the highest observation densities, which, since many distributions are akin to Gaussian (particularly those of birth dimensions), is often the 50th percentile or median[ 5].
Including the birth cohort dimension improves trend studies of mortality and health.
We investigated the effect of including the birth cohort dimension in trend studies of prescription drug use by studying prevalence of statin use among adults.
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