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Furthermore, the expression levels of several genes involved in hemicellulose and lignin biosynthesis were also reduced, while cellulose synthase increased under high compared with adequate N [ 36].
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Furthermore, tyrosine hydroxylase (TH), the rate-limiting enzyme of catecholamine biosynthesis showed diminished activity and newer findings indicate, that TH gene expression was also reduced after antidepressant treatment [47], [48].
The auditory startle response was also reduced.
Placenta weight was also reduced (Table 1).
Moreover, P-Mad expression is also reduced.
HRQoL was also reduced.
Even so, secretion of DHEA reduces with aging, with levels as low 10 20% of the peak concentrations in the elderly, so peripheral estrogen biosynthesis is also significantly reduced.
Transcripts associated with ubiquinone biosynthesis are also slightly reduced, but mostly remain unchanged (Additional file 2).
Besides, aromatic compounds, farnesyl diphosphate, and isoprenoid biosynthesis were also active (Additional file 3: Table S3b).
Oxidative stress, sulphur assimilation of glutathione and proline biosynthesis were also influenced by CuO nanoparticle exposure.
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