The clusters show significant enrichment for many processes crucial for cell growth, including amino acids (e.g., homoserine, serine, methionine, and lysine) biosynthesis, nucleotide, nucleoside and nucleobase interconversions, amine biosynthesis, coenzyme and carboxylic acid metabolic processes as well as tricarboxylic acid (TCA) cycle.
The recent progress in understanding the biosynthesis, the regulation and the cellular transport of itaconic acid has facilitated the optimisation of existing processes as well as the construction of new microbial platforms.
Both Cry and Bma1 regulate a large number of genes involved in general cellular processes as well as in pathways related to major organ-specific function, such as, corticosteroid biosynthesis.
Dimorphic genes in diseased animals belonged not only to the lipid (phospholipid) biosynthesis, but to intracellular (vesicle mediated) transport process as well (Table S7).
Externalization is an equilibration process as well.
The genes were predicted to be involved in a variety of known processes, including carbohydrate metabolism, nutrient transport, and hormone and vitamin biosynthesis, as well as unknown processes.
Essentially, this cohort of NADP+ driven biosynthesis processes corroborates well with the notion that the HEM1_HETKA possesses a NADP+ domain to drive its tetrapyrrole biosynthesis.
In particular, Xiphinematobacter alone showed enrichment for arginine biosynthesis genes, as well as aromatic amino acid biosynthesis (phenylalanine, tryptophan, and tyrosine).
This apparent lack of a diversity of metabolic processes displays a bias in the rhizome toward processes associated with cell wall biosynthesis and remodeling as well as specific specialized metabolic pathways.
Other genes involved in serratane (triterpenoid) and flavonoid biosynthesis as well as hormone biosynthesis and signal transduction were also found.
