Sentence examples for biosynthesis of cell envelope from inspiring English sources
Promising targets for drug development are enzymes involved in the biosynthesis of cell envelope structures such as peptidoglycan, teichoic acids, membrane lipids, or cell wall associated adhesins.
Comparative genomics of the mycobacterial genomes with a focus on genes involved in biosynthesis of cell envelope components was carried out using methodologies viz., sequence similarity, metabolic pathway reconstruction and phylogenetic profiling.
Genes related to the biosynthesis of cell envelope components were up-regulated in young cells only.
Likewise, reactions from cell envelope biosynthesis and membrane lipid metabolism tend to be clustered together because fatty acids created from membrane lipid metabolism are fed into the biosynthesis of cell envelope.
Additionally, alterations to the biosynthesis of cell envelope lipids, caused by the deletion of the cmaA2 cyclopropane-mycolic acid synthase which subsequently lacked the trans-cylcopropane rings in the cell wall mycolic acid, resulted in accelerated host mortality which was attributed to severe lung lesions caused by an excessive inflammatory response (Rao et al. 2006).
The GalU gene encodes for production of UTP-glucose-1-phosphate uridyltransferase, an enzyme that catalyzes the formation of UDP-glucose and is known to have a key role in biosynthesis of cell-envelope-associated carbohydrates (e.g. lipopolysaccharides [LPS] and capsule) in a variety of bacterial species.
The exceptions were the categories of synthesis and modification of ribosomal proteins in both genomes and the biosynthesis and degradation of cell envelope in wBm only.
Mengin-Lecreulx, D. et al. Contribution of the Pmra promoter to expression of genes in the Escherichia coli mra cluster of cell envelope biosynthesis and cell division genes.
The most prevalent (7720 MCS) of these multivalent subsystem signatures target the combination of "Cell Envelope Biosynthesis", "Threonine and Lysine Metabolism", "Alternate Carbon Metabolism", and "Extracellular transport".
Numerous genes related to DNA maintenance and replication, translation, ribosomal biosynthesis and RNA processing as well as biosynthesis of the cell envelope and flagellum and several components of the chemotaxis signal transduction complex were up-regulated only in young cells.
The variant gene-set suggest the existence of alternate routes for biosynthesis of the cell envelope components.
