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The high substrate tolerance of these enzymes towards different FA and alcohol moieties resulted in the biosynthesis of a broad range of MBE.
In particular, Δ11-desaturases contributed significantly to the biosynthesis of a broad range of unsaturated pheromone components in ditrysian species and strongly increased the structural diversity of pheromone precursors [ 6- 8].
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This distribution of the levels of selective constraint has been attributed to upstream genes being involved in the biosynthesis of a broader range of biochemical compounds than downstream genes, and hence being more pleiotropic [ 28], and/or to upstream genes exerting a higher influence over the flux of metabolites along pathways [ 31].
The PHA synthase of R. eutropha H16 exhibits a very broad substrate specificity (Haywood et al. 1989) and catalyzes the biosynthesis of a wide range of different PHAs and PTEs.
The downregulation of a broad range of genes associated with cellular biosynthesis and growth, e.g., ribosomal proteins, also corresponds with the observed 24-h delay in primordium formation associated with A. bisporus MVX infection (4).
Title Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink.
Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink.
The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule.
Biosynthesis of a fluorescent cyanobacterial C-phycocyanin holo-alpha-subunit in a heterologous host.
Reports the cloning of the first enzymes catalysing the biosynthesis of an endocannabinoid, 2-arachidonoylglycerol.
This is indicative of a broader pattern.
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