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Mildronate (3- 2,2,2-trimethylhydrazinium 3- 2,2,2-trimethylhydrazinium 3- 2,2,2-trimethylhydraziniume and is considered an anti-ischemic drug, was designed to inhibit carnitine biosynthesis in order to propionatecumulation of cytotoxic intermediate products of fatty acid beta-oxidation.
In this study, we compared the genomic content of various commensal and pathogenic Neisseria strains, with respect to LOS biosynthesis in order to assess the degree of genomic variability in LOS biosynthetic genes.
We hypothesize that the cell attenuates cobalamin biosynthesis in order to divert intermediates for the biosynthesis of PPIX and bacteriochlorophyll (unpublished observation).
Cancer cells primarily apply glycolysis for cell metabolism, which enables the cells to use glycolytic intermediates for macromolecular biosynthesis in order to meet the needs of cell proliferation.
Consequently, there has been strong interest in the engineering of bioenergy crops, namely grasses, that are more amenable to feedstock conversion, notably by the manipulation of lignin biosynthesis, in order to improve efficiency of the pretreatment process and obtain maximum fuel yield [ 8].
The data about SuSy and AGPPase suggest that in the resistant genotype under infection there could be a redirection of primary metabolism that leads to a reduction of starch biosynthesis in order to provide a strong supply to the hexoses pool.
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A closer look was taken at the terpene biosynthesis pathway in order to see if the precursor pathways were up-regulated by JA.
Here, we build an ordinary differential equation model of the cholesterol biosynthesis pathway in order to investigate how the two regulatory strategies impact upon the behaviour of the pathway.
However, further studies need to be performed, for example, crossing the loss-of-function mutants with various mutants of abscisic acid biosynthesis or signalling, in order to place either gene in the genetic network of gibberellin and abscisic acid signalling.
However, upon metabolic stress, starvation induced autophagy serves to provide substrates for biosynthesis and energy production in order to maintain cellular homeostasis1, 2. The importance of autophagy for cellular and organismal health is showcased by the fact that defects in autophagy have been linked to neurodegeneration, cancer, aging and metabolic syndrome1.
The average RPKM values of unigenes annotated as homologous to fatty acid biosynthesis genes were calculated in order to estimate expression profiles of their corresponding avocado genes (Additional file 4: Table S13).
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