This includes but is not limited by such areas as bioinformatics, biophysical methods and instrumentation, medical biophysics, biosystems, cell biophysics and organisation, macromolecules: dynamics, structures and interactions, and membrane biophysics, channels and transportation.
Principal areas of interest include: structure and dynamics of biological macromolecules; membrane biophysics and ion channels; cell biophysics and organisation; macromolecular assemblies; biophysical methods and instrumentation; advanced microscopics; and system dynamics.
To test this hypothesis, two complementary biophysical methods were utilized.
BIOL W4082 Theoretical Foundations and Applications of Biophysical Methods. 4 points.
CETSA therefore provides a feasable alternative to measure binding to a target where traditional biophysical methods are not possible, for example when recombinant protein cannot be produced.
Herein, using various biophysical methods, we analyze the effect of temperature on the oligomerization of BclXL.
Their secondary and quaternary structures have been studied with spectroscopic and biophysical methods.
Here, we investigated this question by protein engineering and biophysical methods.
The features of several biophysical methods that are commonly used to characterize heterogeneous interactions are compared.
Thus, given the importance of expanded non-coding repeats in other RNA repeat expansion diseases15, we have investigated the secondary structure of the C9orf72 hexanucleotide repeat by biophysical methods to determine whether it forms RNA G-quadruplexes.
To assess whether the G-rich conserved sequence is able to fold into G4, an RNA fragment corresponding to the HCV110-131 region was studied using several biophysical methods.
