Sentence examples for biophysical assays from inspiring English sources

In this work, a series of biophysical assays were performed in order to analyze the effects of a novel two-dimensional carbon nano-material graphene oxide (GO) on the conformational changes of myoglobin (Mb).

Biophysical assays showed that the "de novo" peptide made of non-natural amino acids is helical either in solution or into lipids as tested by Fourier transform infrared spectroscopy and is able to induce liposome fusion.

A method to produce highly purified thrombin from salmon blood is described, and a series of biochemical, cell biologic, and biophysical assays demonstrate the functional similarities and some differences between salmon and human thrombins.

This supports the design and screening of 'reduced complexity' (leadlike) compound libraries, preferably with synthetic handles available for rapid chemical iteration and detected as interesting by careful screening or biophysical assays.

Whether CM2 is a proton channel has not been directly demonstrated by biophysical assays, but it alters the intracellular pH in transfected cells and its transmembrane domain can substitute for that of the influenza A virus M2 protein (Stewart and Pekosz, 2012).

Both electron microscopic reconstructions of Myo1A decorating microfilaments and biophysical assays have demonstrated that this protein is a fully functional plus-end directed myosin [5], [29] and that it binds actin in a manner indistinguishable from that of conventional, class-II myosins [30], [31].

The newly developed biophysical assay provides a tool for monitoring the toxicity levels of drug treatment on animal development.

A generic activation mechanism for this receptor class is presented, which may impact the design of a new generation of biophysical assay systems.

The further analysis and detailed results of these mutants as well as their impact on biophysical assay development for drug discovery can be found in "Method for Rapid Optimization of Recombinant GPCR Protein Expression and Stability using Virus-Like Particles" (Ho et al., 2017) [2].

We tested examples from each of these series in a biophysical assay based on their ability to stabilize PfCDPK1 to denaturation by heat.

35 The type of biophysical assay used to probe a particular cell is dictated by its stiffness and the biological process being studied.