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Therefore, we designed this cross-sectional study in a cohort of children associating lung inflammatory biomarkers and lung function with urinary As levels.
Otherwise, no major associations were found between the different biomarkers and lung function.
The independent associations between different biomarkers and lung function were studied with multiple linear regression.
At 12-month intervals, each child visits the lung function laboratory for measurements of inflammatory biomarkers and lung function tests.
Early measurements of (non-invasive) inflammatory biomarkers and lung function measurements are related to the final diagnosis of asthma.
The purpose of the third phase is to monitor development of respiratory symptoms, inflammatory biomarkers, and lung function in both the experimental and control group.
Similar(51)
In addition, repeated measurements of early predictors, like exhaled biomarkers of inflammation/oxidative stress, and lung function tests are assessed.
The primary research question is whether non-invasive inflammatory biomarkers in exhaled breath and lung function indices can reliably predict asthma at an early age.
The development of a new diagnostic tool for asthma at an early age, based on non-invasive inflammatory biomarkers in exhaled breath, and lung function can lead to an early asthma diagnosis.
Our primary hypothesis is that an early asthma diagnosis is possible using non-invasive measurements of inflammatory biomarkers in exhaled breath (condensate), and lung function tests.
We measured MVF and lung function and all biomarkers in the morning at baseline (day 0) before start of air recirculation, and day 2, 7 and 14 of each exposure scenario.
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