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The study was the first of its kind to use a urinary biomarker of structural damage to the kidney to triage to an intervention and to use the relative average creatinine as an outcome.
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Different patterns of biomarker release imply that different patterns of structural damage involve different pathophysiological mechanisms and may require different therapeutic approaches.
Adalimumab has been shown to significantly suppress serum concentrations of MMP-3, a biomarker that is a significant independent predictor of structural damage progression in AS [ 25, 26].
In conclusion, this study provides further evidence that baseline BML size in an important imaging biomarker associated with greater baseline knee pain, the presence of structural damage at baseline, and OA progression.
While technologies such as echocardiography, magnetic resonance imaging, or multi-gated acquisition nuclear scans provide downstream direct visualization of structural damage in ACIC and complement early abnormal levels of serum biomarkers, the primary focus for this paper will be on circulating biomarkers and multiomics technology.
There's a lot of structural damage".
The thefts can lead to thousands of pounds of structural damage, too.
Non-progression of structural damage.
Primary endpoints were the control of structural damage on radiography.
By contrast measures of structural damage were linked.
Neurofilaments are markers of structural damage to axons, and raised neurofilaments in patients with ICU-AW would suggest structural damage to peripheral nerves.
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