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Computational gene network analysis proposed new biologically tenable molecular pathways of TNF-induced angiogenesis.
Therefore, under TNF stimulus, our estimated edge from IL6 to IL8 is biologically tenable based on published experimental results.
Our approach is semi-automatable (see Methods), but the researcher must: 1) assist in creating the multiple sequence alignments of domains, and 2) select biologically tenable interactions from the final shortlist generated.
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Biologically, it is unparalleled.
By addressing the problem at the gene level, the scope of the analyses is not only computationally tenable, but also reduced to a biologically interpretable unit of interest.
Which solutions are tenable?
Not biologically.
Is the distinction tenable?
But is it tenable?
This is no longer tenable.
His position is not tenable.
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