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The difference in nitrogen concentrations between regions may not appear to be biologically substantial (i.e.: 1.0 1.1% nitrogen in Madagascar and 1.4% in the Neotropics).
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The inter-regulation among subgraphs is also substantial, and biologically significant.
Although there was evidence of substantial difference in relative intron expression across arrays, it was not clear to what extent this reflected biologically significant differences between the samples or merely differences in the arrays or sample preparations.
Is this biologically significant?
However, a substantial minority lack just one or a few genes of the pterin or pABA branches, and detailed analysis of these cases reveals several biologically significant points.
This also further highlights the extent of proportion plasticity in the mammalian brain, and confirms suggestions in the literature7 that mosaic evolution of relative brain partition sizes is widespread, substantial and biologically meaningful.
Our own comparison of the MA versus NI evolutionary gene coexpression networks has revealed that similar properties at a high level of abstraction can obscure substantial and biologically relevant differences at lower levels.
DE is a complex mixture of particulate and gaseous pollutants that comprise a substantial and biologically active fraction of urban ambient air pollution (Health Effects Institute 1995) and is a very appropriate experimental model exposure, especially with the current interest in traffic-related air pollution.
It is still too early to tell whether exposure to these compounds will be associated with puberty, but so far the preliminary data show that exposures can be substantial and perhaps biologically relevant.
However, we find that due to the possible diversity of organisms and environments, and the confounding effects of the atmosphere and clouds, determination of substantial coverage by biologically produced pigments would be difficult with broadband colors alone and would likely require spectrally resolved data.
We employed dim red light as a placebo, reasoning that because the light was dim and because the red part of the spectrum may be relatively inactive biologically [ 5] there would be no substantial biological effect.
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