Sentence examples for biologically relevant models of from inspiring English sources
Developing biologically relevant models of human tissues and organs is an important enabling step for disease modeling and drug discovery.
It remains an open problem to determine how criticality has emerged throughout evolution, i.e. to devise biologically relevant models of network growth that generate critical dynamics.
Experiments on social conflict in rodents have proved a biologically relevant model of stress-induced analgesia: intruders exposed to resident attacks react with decreased nociception [30], [31].
One way to distinguish between these competing hypotheses is to simulate our experimental system with a biologically relevant model of population dynamics that is broadly applicable to several species and does not include any specific features of Drosophila life-history or laboratory ecology.
We utilized a biologically relevant model of experimental myositis, which can be elicited by immunization of wild-type mice with a synthetic sequence corresponding to a well-characterized autoantigen, HisRS [ 11, 12].
We have shown that the complex bifurcation structure of the model matches with the dynamical changes seen in a biologically relevant model for variations of both excitatory and inhibitory strengths [4].
Articular cartilage explants subjected to pro-inflammatory cytokines provide a biologically relevant model to study the time-dependent release of ECM degradation-fragments [ 10- 12].
Moreover, in case of TB, guinea pig has emerged as the most preferred and biologically relevant model to investigate TB pathogenesis and therapy [ 11].
Ultimately, it is unlikely that a single kinase system integrates all pro-hypertrophic signalling pathways, emphasizing the need for biologically relevant models in the characterization of relevant cardiomyocyte signalling and in determining the overall effects of single kinase interventions.
