Sentence examples for biologically relevant complexes of from inspiring English sources
Major recent developments include the synthesis of a number of unusual and biologically relevant complexes of copper and iron using elaborate N-donor and O-donor ligands.
The substrate analog-bound structures that represent the biologically relevant complexes of proofreading domains invariably occupy the deepest available pocket having a striking surface complementarity.
The quaternary structures of proteins are the bases of their physiological functions (Jones and Thornton 1996; Henrick and Thornton 1998; Krissinel and Henrick 2007), and thus it is indispensable to know the biologically relevant complexes of proteins to understand their functions at the molecular level.
Three biologically relevant complexes containing derivatives of Compstatin (Sequence 11: Ac-ICV OMW QDWGAHRCT-NH2, Sequence 23: Ac-ICV OMW QDWGAHRCT-NH2d Ac-ICV OMW QDWGAHRCT-NH2CT in Table 3) were aSequencefor their interactions through multiple longer-time molecular dynamics simulations.
Thirdly, the biologically relevant complexes exhibit a remarkable redundancy of observation wherein the presence of ligand is observed in every monomer.
Important features of antibodies for target validation studies are recognition of the antigen in natural conformations and biologically relevant complexes.
Our analysis highlights features of the earlier binding modes that are totally uncharacteristic of biologically relevant complex.
Lastly and most importantly, a biologically relevant complex is expected to have a substantial number of interactions between the ligand, and the enzyme and the residues involved in these interactions must be evolutionarily conserved.
Going by the general principles of enzyme-substrate interactions, the ligand in a biologically relevant complex is expected to bind in the deepest available pocket with strong surface complementarity and chemical compatibility with a conserved network of interactions.
In an additional experiment, we wished to confirm the capability of our platform to detect specific microRNAs in a biologically relevant complex background.
In summary, the dimeric aFGF Cys2 heparin complex might represent a biologically relevant complex in physiological media.
