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Moreover, plasma ACTH becomes biologically ineffective which leads to suppression of the synthesis and release of cortisol from ACTH-stimulated adrenocortical cells (Fig. 2) [ 20].
In the form of a diphosphate prodrug, ara-C was found to be protected from the cytosine deamination, which leads to the biologically ineffective ara-U.
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We argue that programs designed specifically to monitor biodiversity, although sometimes criticized as inefficient and ineffective, are statistically and biologically robust in the long term, especially compared to the status quo.
In contrast, crosslinked materials have long diffusion lengths into the gel compared with those between cells on the surface of the material, which may make them ineffective at sequestering pro-inflammatory cytokines on biologically relevant timescales.
The myelodysplastic syndromes (MDS) comprise a haematologically and biologically diverse group of stem cell disorders characterized by accelerated apoptosis and ineffective haematopoiesis that lead to functional haematopoietic failure (Faderl & Kantarjian, 2004; Catenacci & Schiller, 2005; Hofmann & Koeffler, 2005; Kurtin, 2006).
17 18 Similarly, in biologically directed treatments, such as for cancer treatments, it is possible that a treatment will be effective in one subgroup and ineffective in another.
Not biologically.
And ineffective?
TSEs are biologically unique.
They are, biologically, younger.
Is this biologically significant?
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