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Although, it is unclear, however, whether transcription factors actually bind to these sites and elicit biologically functional changes in gene expression.
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The overwhelming support for selection-driven convergence in SP1 and its binding sites shows that a large multi-gene regulatory system can indeed undergo biologically relevant change, whether or not the functional changes in SP1 involved changes in regulatory topology.
The most likely explanation for the rapid development of ExMV research, which has been followed by an exponential increase in the number of published papers in subsequent years, has been the demonstration that these small cellular membrane fragments transfer RNA species and several other biologically active molecules between cells and thus may induce functional changes in the target cells [13 15].
Functional changes in neuronal systems induced by phencyclidine administration.
The anaerobic- A1), anaerobic- A1nd oxic-(O) anoxic- A2sludge sanoxic- A2e collected respectively from the corresponding biologicandy functional zOnes in Cactivatedoxidation ditch sludgesamples
Importantly, lipoprotein particles are biologically functional only in their native state in an aqueous environment.
Proteins are often the biologically functional elements in cellular networks; thus, many types of data can be mapped to and through proteins as a common biological object.
The pertussis toxin remains biologically functional despite these changes (24 ).
Finally, the uORFs per se may be biologically functional, in terms of either their peptide products or their regulatory roles.
Hypericum perforatum is a plant rich in biologically functional polyphenolic phytochemicals.
Hypericum triquetrifolium Turra is a plant rich in biologically functional polyphenolic phytochemicals.
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